Posted by kinasepro on May 2, 2009
Millenium’s beta-carboline’s aren’t new, but the structure of the Phase one IKK-B inhibitor hasn’t been released afaik. Currrently in the Takeda pipeline via last years takeover.
Read the rest of this entry »
Posted in IKK, Millenium, Takeda | Leave a Comment »
Posted by kinasepro on July 4, 2007
US20070149533 is a Raf app from Millennium. I see it as a napthalene – amide cousin to the Birb and Nexavar style ureas. Amgen’s been in the area but not right on top.
Good thing too, b/c you know, I was’t really feeling the whole ‘hydrocinnamides’ thing in US20060160803
Posted in Millenium, RAF | Leave a Comment »
Posted by kinasepro on June 12, 2007
So Millennium is advancing MLN-8237 to phase one, but if the structure I have for MLN-8054 is correct:
… then I’m crossing my fingers that MLN-8237 isn’t the methyl ester! All I can find is: US/2005/0256102.
Posted in Aurora, Millenium | 4 Comments »