Ki 0.38 nM
Archive for the ‘CK2’ Category
Posted by kinasepro on November 6, 2007
c-Met + Indolinone: 2RFS; Amgen
c-Met + pyrimidone: 2RFN; Amgen <- Clearly the highlight of the day, but no image from me yet. I’m looking at it wondering where did all the polar contacts go? Peculiar structure, but noteworthy as the first published structure in the xl-880/kirin/bms/genentech/array/methylgene acyl urea isostere genre.
CK2: 2RKP: 1.56A
Posted by kinasepro on April 30, 2007