KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for the ‘Fgf’ Category

E7080

Posted by kinasepro on May 29, 2007

O=C(C1=CC2=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C=CN=C2C=C1OC)N

US20070117842 is a polymorph application, and there’s been a fair amount of IP activity around the compound. Indications are its E7080: an oral PhI Vegf, FGF, Pdgf, C-Kit, etc compound which first touched down in WO/2004/080462.

Posted in c-Kit, Eisai, Fgf, PDGFR, VEGF | 2 Comments »

WO/2007/019884

Posted by kinasepro on February 26, 2007

Roche’s got a Vegf/FGF app in WO/2007/019884

NC1=C(C(COC2=CC=C(Br)C=C2)=CS3)C3=C(C(NCCCCN4CCCC4)=O)C=N1

They’ve been around since ’05 though

Posted in Fgf, Roche, VEGF | 1 Comment »