KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for the ‘EphB4’ Category

PDB Update

Posted by kinasepro on October 29, 2008

Aurora A + 680: 3E5A; Protien Sci

Aurora B: 2VGO; Mol Cell Ther

SRC: 3EL7 & 3EL8; Chem Biol;

EPHB4: 2VWX; 2VWY; 2VX0, 2VX1

Posted in Aurora, EphB4, PDB, SRC | 2 Comments »

AZ’s Bis-Morpholine

Posted by kinasepro on September 4, 2008

+ XRPD on multiple salt forms of this EphB4 inhibitor:

OCC1=CC=C(C)C(N(C2=NC(NC3=CC(N4CCOCC4)=CC(N5CCOCC5)=C3)=NC=C2)C)=C1

WO/2008/104754

Posted in Astra, EphB4 | Leave a Comment »