KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for February, 2009

Lexicon’s got Limk2

Posted by kinasepro on February 18, 2009

LX-7101 in here 20090042893?

lex

Reminds of Exel

Posted in Lexicon | Tagged: | Leave a Comment »

CP-690,550

Posted by kinasepro on February 10, 2009

CP-690,550 is Pfizer’s Ph3 Jak inhibitor. J Mol Biol. JAK2: 3FUP & JAK1?: 3EYG

N#CCC(N1C[C@H](N(C)C2=C3C(NC=C3)=NC=N2)[C@H](C)CC1)=O

Thanks Cytopia & no I didn’t forget 3EYH

Posted in JAK, PDB | 3 Comments »

Janssen’s got PLK4

Posted by kinasepro on February 9, 2009

COC(C=C(NC1=NC=NC2=C1C(C3)=CN2)C=C4OCC(N(C)CCCN3C)=O)=C4OCCCN5CCOCC5

WO/2009/016132

Posted in J&J | Tagged: | Leave a Comment »