KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for the ‘PDK1’ Category

Merck’s got Azaindoles

Posted by kinasepro on May 4, 2009

pan-Jak:

CCN(N=C1)C=C1C2=CN=C3C(C(C4=NC(OC5CCNCC5)=CN=C4)=CN3)=C2WO/2009/054941

Posted in JAK, Merck & Co., PDK1 | Leave a Comment »

R & D @ B I

Posted by kinasepro on September 13, 2008

With BIRB-796 a distant memory, BIBW-2992 in ph3 and given the new name Tovok, BIBF-1120 headed into ph3 and given the name Vargatef,  BI-2536 in multiple Ph2s, a new Ph1 Aurora inhibitor, and another backup PLK1 inhibitor undisclosed, but likely in-clinic or clinic-bound – what could possibly be next?

I can haz pyrimidines

PDK mod prolly from Berlex

Posted in BI, PDK1, PKC, Plk1 | 2 Comments »