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Archive for the ‘Sunesis’ Category

Biogen Nominated…

Posted by kinasepro on July 14, 2009

… A RAF candidate & Sunesis got a milestone,

In August 2004 the companies entered into a collaboration to discover and develop small molecule cancer therapeutics targeting kinases, a family of cell signaling enzymes that play a major role in the progression of cancer. The research term of this collaboration ended in June of 2008. Sunesis retains an option to participate in the co-development and co-promotion of the Raf kinase inhibitor resulting from this collaboration.

Likely derived from WO/2009/006389WO/2009/006404



Posted in Biogen, RAF, Sunesis | 2 Comments »


Posted by kinasepro on May 12, 2009

Sunesis’ Ph1 Aurora inhibitor:

Related PDB’s: 3D15,3D14,3D2I,3DJ7
Amgen’s related pyrimidine: 3EFW

Read the rest of this entry »

Posted in Aurora, Sunesis | 1 Comment »


Posted by kinasepro on March 6, 2007

‘nother Phase1 underway CDK2,7,9 formerly BMS-387032 for

patients with advanced B-cell malignancies


press release and an ‘old’ J Med Chem.


Posted in CDK2, Sunesis | Leave a Comment »


Posted by kinasepro on March 3, 2007

Sunesis submitted an IND application for SNS-314 the other day. It’s an Aurora inhibitor, likely coming out of: WO/2007/013964 / US20070027166


update:: poster here

the poster indicates 314 is <450 mw


Posted in Aurora, Sunesis | Leave a Comment »