KinasePro

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Archive for November 21st, 2007

VX-680, VX-667: Done

Posted by kinasepro on November 21, 2007

VX-680 halted as:

one patient experienced QTc prolongation.

O=C(C3CC3)NC(C=C4)=CC=C4SC1=NC(N2CCN(C)CC2)=CC(NC5=NNC(C)=C5)=N1

and the follow-on, VX-667:

Failed to meet pharmacokinetic objectives in a Phase 1 trial

Posted in Aurora, Merck & Co., Vertex | 15 Comments »