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Archive for the ‘pi3k’ Category


Posted by kinasepro on December 10, 2006

G’day Kinacia (formerly Thrombogenix) I see you guys made a splash with TGX-221, a selective Pi3K-b inhibitor. And now it looks like you’ve been fine tuneing. I’m thinking the Bioorg Med Chem Lett will look something like:

LY294002 is: 1E7V

221: WO/2001053266


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Posted by kinasepro on November 3, 2006

Hi Serono, Nice Nature Reviews DD article:

PI3K crystals to date: 1E7U, 1E7V, 1E8W, 1E8X, 1E8Y, 1E8Z, 1E90, 2F4J, 2A4Z, 2A5U

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