Posted by kinasepro on August 7, 2009
Astex has released data about their AKT program, including a PDB, but I have omitted that they appear to have dropped the strutcture of their candidate in WO/2008/110846
This entry was posted on August 7, 2009 at 10:54 pm and is filed under AKT, Astex.
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It is a bit cheeky to call it “AKT inhibitor” with similar or even better potency against PKA, p70SK and Rock.
Patent itself covers the usage in conditions linked to either of those kinases !
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