Kinase Chemistry – Just a year and a half behind the times.

What do…

Posted by kinasepro on July 10, 2009

…the Bee Gee’s and R406 have in common?

R-788 (a prodrug of R-406) has shown promise in a Ph2b trial. Partner Plz?

riglstill no BMCL

2 Responses to “What do…”

  1. ATP->ADP said

    There may not be any BMCL till it is partnered 😉

  2. Gurgle said

    The safety data is alarming. Molecule looks DOA to me for RA…might fly for cancer. You should also check out the reproductive tox with R788 recently disclosed by Rigel and ascribed to Ret as an off-target.

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