KinasePro

Kinase Chemistry – Just a year and a half behind the times.

JNJ-

Posted by kinasepro on May 8, 2009

WO/2009/058801 is a use application for the pictured c-FMS inhibitor.

O=C(CN(C)C)N(CC1)CCC1C2=CC=C(NC(C3=NC(C#N)=CN3)=O)C(C4=CCCCC4)=C2

it’s JnJ-141 in the application, but does it have a dev #?

2I1M suggests a binding mode:

jnj-art-1

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