KinasePro

Kinase Chemistry – Just a year and a half behind the times.

CP-690,550

Posted by kinasepro on February 10, 2009

CP-690,550 is Pfizer’s Ph3 Jak inhibitor. J Mol Biol. JAK2: 3FUP & JAK1?: 3EYG

N#CCC(N1C[C@H](N(C)C2=C3C(NC=C3)=NC=N2)[C@H](C)CC1)=O

Thanks Cytopia & no I didn’t forget 3EYH

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3 Responses to “CP-690,550”

  1. weirdo said

    There is something just so generally appealing about a PDB file named “FUP”. The fact that is a clinically important molecule makes it all the more so.

  2. Orgmed said

    Great work from Monsah/Cytopia. What could be the status of CYT387.

  3. weirdo said

    CYT387 still not quite in the clinic, but haven’t heard it’s off track.

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