KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Astra’s got IGF1R

Posted by kinasepro on October 2, 2008

Its not in the pipeline, but it is a candidate. WO/2008/117051 has xrpd, and lots of data.

CC1=CC(NC2=NC(N3CCC[C@H]3C4=NOC(C5=NC=CC=N5)=C4)=NC(OC)=C2)=NN1

10x enough?

‘o’; mode

Advertisements

One Response to “Astra’s got IGF1R”

  1. Orgmed said

    HAcceptors 11, PSA 131, High PPB?. Interesting compound with very unique C-2 substituution, but very common C-4 substitution (one like VX-680).

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

 
%d bloggers like this: