Kinase Chemistry – Just a year and a half behind the times.

At least its free…

Posted by kinasepro on August 20, 2008

The new ‘Perspective‘: Some useful information bracketed by useless commentary.

Affinity is not even a check-box on the road to an approved drug.  What’s stopping 99.9% of real compounds coming from real programs isn’t potency.  This makes a discussion of how many hydrogen bonds to the hinge are in approved drugs totally irrelevant.

Fact Check:

>> Ruboxistaurin is not an approved drug.

>> Fasudil is only approved in Japan.

>> And you forgot Tasigna


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s

%d bloggers like this: