KinasePro

Kinase Chemistry – Just a year and a half behind the times.

TG-101348

Posted by kinasepro on December 7, 2007

Targegen’s got a press release:

Plans to initiate a multi-center clinical trial of TG101348, an internally discovered, oral, potent, and highly selective JAK2 inhibitor in January, 2008

A poster at ASH:

…Dual-Acting JAK2/FLT3 Small Molecule Kinase Inhibitor for the Treatment of AML

and some pyrimidines in WO/2007/053452:

CC1=CN=C(NC3=CC=C(OCCN4CCCC4)C=C3)N=C1NC2=CC=C(Cl)C(OC)=C2

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