This entry was posted on November 30, 2007 at 11:42 pm and is filed under PDB, SGC.
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That’s sure not your average drug molecule! A piperidine spiro fused to a multiply-substituted beta-carboline ring system, and a stereocenter adjacent to the quaternary center. Except for the chlorines, this looks more like what you’d expect to see in an alkaloid than a drug candidate.