Kinase Chemistry – Just a year and a half behind the times.

Bayer ‘n Egf

Posted by kinasepro on October 2, 2007

Set of covalent ErbB inhibitors from Bayer:




3 Responses to “Bayer ‘n Egf”

  1. Is that an aniline I see? Heathens! Burn them!

  2. DrBaritone said

    Derived from benzyle indole/indazole patents, Glaxo Wellcome 1996. Think of something new!

    erbB irreversible inhibitors,….why?

  3. Radiochemist said

    Ever heard of specific mutations in the binding pocket leading to resistance to Iressa?

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