KinasePro

Kinase Chemistry – Just a year and a half behind the times.

WO/2007/96259

Posted by kinasepro on September 5, 2007

Roche has a 2nd gen series of hydantoins as MEK inhibitors with WO/2007/96259:

IC1=CC=C(NC([C@H](C(C)C)N2C([C@@H]([C@@]3=CC=C(OCC(N4CCCC4)=O)C=C3)NC2=O)=O)=O)C(Cl)=C1

 > hydroxamates?

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