Kinase Chemistry – Just a year and a half behind the times.

Amgen ‘n Aurora

Posted by kinasepro on August 2, 2007

WO/2007/087276? How ’bout that.


4 Responses to “Amgen ‘n Aurora”

  1. ashujo said

    Indirubin Aurora inhibs from J. Med. Chem. ASAP. In case you missed.

  2. That was me by the way

  3. kinasepro said

    Unless it gives me a truly visceral reaction, I don’t cover the ‘primary’ literature…

    “Several drugs potently inhibiting such receptor tyrosine kinases have reached clinical trials, and two compounds, imatinib (Gleevec) and gefitinib (Iressa), are already in clinical use as chemotherapeutic drugs.9”

    WTF? Academic literature that suggests there are only 2 “receptor tyrosine kinase” inhibitors on the market – And one of the two they choose has an FDA warning saying that it’s teh sux…

    taptaptap is this thing on?

    I could go on, but its better for everyone if I stop now.

  4. The intros to some of these things are getting trite….and I thought you usually cover the primary literature on the bar to the bottom right. But it’s cool…you are doing a swell job anyway…I just pitch in once in a while. It seems some of these give you “visceral pain”!

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