KinasePro

Kinase Chemistry – Just a year and a half behind the times.

IKK-b or Jak?

Posted by kinasepro on June 4, 2007

So Merck’s got WO/2007/061764 and the wordplay makes me think the bit about JAK is just a diversion and that the primary target is IKK-b.  You have to squint a little to see the similarity with the Millennium series, but as usual: what do I know.  Interesting series none-the-less.

NC1=NC=C(C(N)=O)C2=C1C3=CC=C(C(F)(F)F)C=C3S2

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