KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Biogen’s new stuff

Posted by kinasepro on May 30, 2007

So what is going on with TGF-β anyhow. GSK WO/2002/062794 , Lilly WO/2002/094833, WO/2004/050659, & WO/2005/092894, Biogen WO/2004/072033, and Pfizer (WL) WO/2004/026306 have all been playing in the pyrazole / TGF sandbox but all I’ve seen is some pretty pictures and a few J. Med Chem.’s

Biogen’s got a new one with WO/2007/059359, but not a single mention in during “R&D day.” 😦 Its either supersekrit, or DOA.

O=C1N(C)N(C)C(C2=CC3=NC=CN=C3C=C2)=C1C4=CC=CC(S(=O)(N)=O)=C4

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