KinasePro

Kinase Chemistry – Just a year and a half behind the times.

VQD-002

Posted by kinasepro on May 2, 2007

Vioquest recently gave an update on their ph i/iia study with this here nucleotide. Nearly as old as ATP itself, the compound was made new again by a diagnostic screen for cancers overexpressing AKT.

NC1=NN(C)C2=C3C(N([C@H]4[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O4)O)O)C=C13)=NC=N2

Also goes by: API-2, NSC-154020, TCN-P, and triciribine phosphate. and yeh, somebody got the structure wrong in Cancer Res. 04, 4394

(KSR v. Teleflex? suck it.)

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