KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Nexavar ®

Posted by kinasepro on April 8, 2007

Nexavar ®, sorafenib tosylate, BAY-439006

O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1)NC

Discovery: Bayer WO/2000/042012
US Approval: December 2005

wiki; Org.Proc.Res.Dev. ’02, 777

PDB: 1UWH; 1UWJ; 2HZN

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