KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Roche ‘n Raf

Posted by kinasepro on March 19, 2007

US20070060607 is ‘nother thienopyridine application from Roche. The listed in vitro assay uses c-Raf, but selectivity isn’t described.

O=C(C1=CN=C(N)C2=C1SC=C2COC3=C(C)C=CC(NC(C4=CC=C(Cl)C=C4)=O)=C3)NCCO

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