KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Tykerb: a go

Posted by kinasepro on March 14, 2007

After announcement of the positive Ph3 it seemed like just a matter of time, and that time has come. Tykerb gets FDA approval in combination with Xeloda for treatement of advanced metatatic breast cancer where the cancer overexpresses Her2 as a second line therapy. And yes that is a mouthful… a 1.25g/d mouthful, worth eventually an estimated 1b/y.

ClC1=CC(NC2=NC=NC3=CC=C(C4=CC=C(CNCCS(=O)(C)=O)O4)C=C32)=CC=C1OCC5=CC(F)=CC=C5

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One Response to “Tykerb: a go”

  1. Very impressive. 1.2 g tolerated.

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