KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Pfizer’s Latest Vegf Candidate

Posted by kinasepro on February 16, 2007

Polymorphs and salt forms in WO/2007/017740

looks like the bis-maleate salt is preferred.

smiles_O=C(C1=C(C)OC2=CC(OC3=C4C=CC(OCCN5CCOCC5)=CC4=NC=C3)=CC=C12)NC

compound via Agouron

Advertisements

2 Responses to “Pfizer’s Latest Vegf Candidate”

  1. Egon said

    Hi KP,

    I saw you have the SMILES in the , which is a good start, but impossible for a machine to recognize. Can we think of something a bit more semantic? You could put in the InChI instead (*), or make it alt=”SMILES:O=C(C1=C(C)OC2=CC(OC3=C4C=CC(OCCN5CCOCC5)=CC4=NC=C3)=CC=C12)NC” or so. I would just love to see your kinase inhibitors show up on [1].

    Egon

    1.http://wiki.cubic.uni-koeln.de/cb/inchis.php

    *) e.g. you can create them via the pubchem website via their drawing tool

  2. kinasepro said

    Hello again Egon.

    A) fyi, The wordpress spam-filter always grabs your posts… not sure why, but consider emailing if the blog ignores you.

    B) It may just be a wordpress phenomena, but the the colon in alt=”smiles: in the html phrase:

    {img src=”http://jpeganywhere.com/” alt=”smiles:O=C(C1=C(C)OC”}

    for some reason is not handled very well. How about an underscore _ ?

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

 
%d bloggers like this: