Kinase Chemistry – Just a year and a half behind the times.

GSK – More Aurora Active Pyrimidines

Posted by kinasepro on February 16, 2007

Here’s another Aurora application: WO/2007/018941


sensing a pattern?

4 Responses to “GSK – More Aurora Active Pyrimidines”

  1. milkshake said

    I guess this Aurora series had a common ancestor with their Src/Abl aminothiazole compounds

  2. kinasepro said

    hmm… not ringing a bell. You don’t mean dasatinib?

    Mebbe the cyclacel stuff…

  3. milkshake said

    No, I mean Dasatinib. They were very active in 5-aminothiazole-2-acid amides and this one is not too far off. Common ancestor, not an outgrowth of Dasatinib,

  4. kinasepro said

    pyrimidines bore me =(

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