KinasePro

Kinase Chemistry – Just a year and a half behind the times.

WO/2007/009898 (Nerviano)

Posted by kinasepro on January 31, 2007

Nerviano’s been looking at the thienopyrroles since the Pharmacia IT days, but the priority date on this one is 7/05… So whats new I ask? Well, appears they found some ortho substituents that work.

O=C(C(S1)=CC2=C1NN=C2NC(C3=CC=CC=C3N([H])C(C)=O)=O)NC(C4=CC=CC=C4)(C)C

Most notably amides and benzamides
Hmm… See a little quinazoline isostere in these?

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