Kinase Chemistry – Just a year and a half behind the times.


Posted by kinasepro on January 5, 2007

Making some bold claims, Innovive gets orphan status for INNO-406 / NS-187



3 Responses to “INNO-406”

  1. milkshake said

    A second generation of a successful drug does not necessarily has to be from the same company – look what Sepracor did.

    Also, it often takes a very small change to get a superior PK or selectivity profile.

  2. kinasepro said

    No doubt, and my hat’s off to Nippon Shinyaku Co, but that just strikes me as the kind of thing you make and claim on the first, or at least the second go round…

  3. Discoverydock said

    Small change, gives big difference. It happens in Kinase drug discovery. To get this small change, they might have spent years of work!!!! No surprise.

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