Kinase Chemistry – Just a year and a half behind the times.


Posted by kinasepro on January 4, 2007

>> update >>   An Exelixis Mek application WO/2007/044515 published 4/19/07

So did the IND and deal actually beat the patent application? Either that or I’m missing something, because I can’t find it.

“XL518 is the second Exelixis compound designed to inhibit the RAS/RAF/MEK/ERK pathway with high potency and specificity, and the first to specifically target MEK,”

They’ve got an interesting RAF application in the stable, but I was under the impression that was the one to house the XL281 series.

hat tip: Xcovery, but of course.

2 Responses to “XL518”

  1. frozenbeef said

    You are not missing anything, the patent has not published…they did the deal without it publishing

  2. Kinasepro said

    Looks like it just published… WO/2007/044515

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