Kinase Chemistry – Just a year and a half behind the times.


Posted by kinasepro on December 21, 2006

This is a process application via GSK for a P38 inhibitor. There’s a number of applications in this series since ’03. but to the best of my knowledge no publications.


That’s usually a sign.


2 Responses to “WO2006134382”

  1. ebola1 said

    I’m sure the isoxazole will make it through development.
    Time to publish all of those old programs.

  2. milkshake said

    This one is probably binding in the same mode as Pharmacia 2-methyl-4-(o,p-difluorobenzyloxy)-1-aryl-5-bromopyrimidinon-6-ones

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