Kinase Chemistry – Just a year and a half behind the times.


Posted by kinasepro on December 2, 2006

Hi AstraZeneca, 278 examples of Aurora kinase inhibitors? Nice.

The amino pyrazole quinazolines are known, but these take it to a whole ‘nother level. See also: WO2006067391 and some earlier stuff: WO2004093880


One Response to “US20060270692”

  1. Whats the MW of that beast? I guess they havent been going down the road of building in oral availability to their earlier candidate (ZD1152?), have they?

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