Kinase Chemistry – Just a year and a half behind the times.

Archive for November 24th, 2006

BMS-354825 vs. VX-680

Posted by kinasepro on November 24, 2006

At least the PDB gave us something to look at a few days ago. Here’s a super-cool alignment of dasatinib in Abl to VX-680 in an abl mutant.

Posted in Aurora, bcr abl, BMS, Vertex | Leave a Comment »

World ‘o’ kinases takes the weekend off.

Posted by kinasepro on November 24, 2006

Not Kinasepro mind you, we’re here furiously searching for the latest and greatest in kinase related non-literature literature. It’s the rest of the world that seems to have taken this Thanksgiving weekend off. News agencies: nothing worth reporting. The USPTO: closed for the holiday so no thursday list. Its so bad that I’ve been forced to pour over a few German applications. No offense Merckle Biotech, but its a little hard to get excited about a couple p38 inhibitors that look like:

Posted in General Interest | Leave a Comment »