Posted by kinasepro on November 19, 2006
Tag Cytopia, I see you nominated a c-fms inhibitor, neet-0, but no patent app published yet? There’s an article in FASEB, but whats say we stick with calling it c-fms, eh? If you want to get creative, lets go with c-FMS, or fms, or maybe even CFMS, but CSF-1R? Aww c’mon, we’ve got enough names to keep up with 😦 How about a little standardization here, people?!
From application WO2004054977 it appears the cross screens for your JAK2/3 programs included c-fms, hck, zap70, fes, and abl. I like it, nice way to determine selectivity profile, and to find the serendipitous hit here and there. Good show, my guess is you found something with a little fms selectivity.
Also, I’m a little behind the times, so a belated congrats on partnering your JAK3 program with Novartis.