KinasePro

Kinase Chemistry – Just a year and a half behind the times.

US20060258706

Posted by kinasepro on November 17, 2006

Hi Celgene. Stylish JNK inhibitor you’ve got there. Kinasepro notes that you guys have been on this since WO2002010137, US2004127536, US2005009876, and WO2006058007 with three named compounds (cc930, cc401, and cc359) a little competition from Esai (WO2002083648) and now without a lot of fanfair the publication of this ‘solid forms of a JNK inhibitor’. My guess is that its your phase ii compound:

C1(NN=C2C3=CC(OCCN4CCCCC4)=CC=C3)=C2C=C(C5=NN=CN5)C=C1

Since you don’t ask anybody to look at DSC, TGA, XRPD, etc. unless you’ve nominated and you really don’t need to patent the solid forms stuff unless your really confident in the comopund.

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