Hey look what I got:
Yah, its the disclosure of the discovery of PHA-848125. Not only that, its a pretty good poster. This also means I was wrong again!
Archive for the ‘Nerviano’ Category
Postcards from Vienna…
Posted by kinasepro on October 1, 2008
Posted in CDK, Nerviano | 7 Comments »
Nerviano ‘n CDK
Posted by kinasepro on August 19, 2007
>> Update >> its really PHA-848125
WO/2007/90794 is a CDK inhibitor in combination with yada yada… from Nerviano. The single compound claimed is pictured and potentially the phase one compound: PHA-793887.
Discovery: Pharmacia IT WO/2004/104007
Posted in CDK, Nerviano | 4 Comments »
WO/2007/009898 (Nerviano)
Posted by kinasepro on January 31, 2007
Nerviano’s been looking at the thienopyrroles since the Pharmacia IT days, but the priority date on this one is 7/05… So whats new I ask? Well, appears they found some ortho substituents that work.
![O=C(C(S1)=CC2=C1NN=C2NC(C3=CC=CC=C3N([H])C(C)=O)=O)NC(C4=CC=CC=C4)(C)C](http://img260.imageshack.us/img260/6337/nervianomq7.jpg)
Most notably amides and benzamides
Hmm… See a little quinazoline isostere in these?
Posted in Aurora, Nerviano | Leave a Comment »
Aurora dev compounds
Posted by kinasepro on January 22, 2007
Crimson Canary has a Rockin spreadsheet on Aurora inhibitors in development.
Posted in Aurora, Nerviano | 3 Comments »
Plethora ‘o’ PDB’s
Posted by kinasepro on November 15, 2006
C3=CC=CC=C3)=O)C2)=NN1)C4=CC=C(N5CCN(C)CC5)C=C4](http://img209.imageshack.us/img209/4488/2j50vc5.jpg)
Posted in Nerviano, PDB | Leave a Comment »
