WO/2009/042806 & WO/2009/042711
process app.
Archive for April 2nd, 2009
BI-2536
Posted by kinasepro on April 2, 2009
BI’s Ph2 PLK1 inhibitor
![O=C(C1=CC=C(C(OC)=C1)NC2=NC=C(N(C3=O)C)C(N([C@@H]3CC)C4CCCC4)=N2)NC5CCN(CC5)C](http://kinasepro.files.wordpress.com/2009/04/bi-2536.jpg?w=444&h=244 "bi-2536")
IV / 0.8 nM
Posted in BI, Plk1 | Leave a Comment »
ON-01910
Posted by kinasepro on April 2, 2009
Onconova’s IV Ph2 PLK1′inhibitor’
![O=S(CC1=CC(NCC(O[Na])=O)=C(OC)C=C1)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O](http://kinasepro.files.wordpress.com/2009/04/on-019010.jpg?w=444&h=244 "on-019010")
“…a new chemical entity that arrests cancer cells in G2/M by modulating mitotic regulatory pathways including polo-like kinase 1 (Plk1).” via WO/2008/088803
Posted in Plk1 | 8 Comments »
