KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for October 2nd, 2007

Pdb update

Posted by kinasepro on October 2, 2007

2qoq: 1.6A structure of Epha3 & ‘juxtamembrane’ region via SGC: (looks like I missed this series which was released a few months back starting with 2GSF.

This week there’s also:
2P55: Mek w/ Cl-1040 analog via Pfizer

Posted in PDB | Leave a Comment »

$

Posted by kinasepro on October 2, 2007

So what are they worth?  TotallyMedicinal’s got the low-low.

TY TM for data: mirrored here.

Posted in Approved | Leave a Comment »

Bayer ‘n Egf

Posted by kinasepro on October 2, 2007

Set of covalent ErbB inhibitors from Bayer:

O=C(/C=C/CN(CC)C)N(CC3)CC2=C3C1=C(NC4=CC(C=CN5CC6=NC=CC=C6)=C5C=C4)N=CN=C1S2

WO/2007/109279

Posted in Bayer, EGF | 3 Comments »

 
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