KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for February 9th, 2007

LX1032 ?

Posted by kinasepro on February 9, 2007

While not telling us which one they had a ‘protein kinase’ application publish today.

WO/2007/016674 or US20070032501

I’m guessing AKT PH domain

O=C(N)C1=C(F)C=C(C2=CC(C3=CC=CC(C4CCN(C(C)=O)CC4)=C3)=CN=C2N)C=C1F

13 examples, 7 authors.

I don’t know enough about the biology to know if AKT inhibition leads to reduced peripheral serotonin levels. If so, I’d say a few puzzle pieces are falling together.

Posted in Lexicon | 3 Comments »

The Thursday List

Posted by kinasepro on February 9, 2007

    US applications:

20070031956 PIM1 Xray
20070032403 ITK Xray BI
20070032478 Allergan
20070032487 Pi3K Novartis
20070032492 P38 BI
20070032495 CDK2 Schering-Plough
20070032501 Lexicon
20070032507 PKC Novartis
20070032508 EGFR AstraZeneca
20070032512 EGFR OSI
20070032513 EGFR AstraZeneca
20070032514 Aurora BI
20070032515 Alk Exelixis
20070032518 CDK2 CDK5 AMGEN
20070032519 c-fms Plexxicon
20070032528 Vegf FGF Novartis/chiron

    World Applications

WO/2007/016228
WO/2007/016674 Lexicon
WO/2007/016392 BMS
WO/2007/016286 Janssen
WO/2007/016228 Novartis
WO/2007/015923 VERTEX
WO/2007/015871 Novartis
WO/2007/015877 P38 KALYPSYS
WO/2007/015837 Chk1 Merck & Co
WO/2007/015064 AstraZeneca
WO/2007/014707 Roche

Posted in biotech | Leave a Comment »

 
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