KinasePro

Kinase Chemistry – Just a year and a half behind the times.

Archive for January 16th, 2007

PDB Update

Posted by kinasepro on January 16, 2007

Its been a slim last few weeks… Things are looking up though:

5 New Abl Xrays care of Novartis: 2HYY; 2HZ0; 2HZ4; 2HZI; 2HZN (medium-low rez and most have been published in one form or another…)

1 New “Vertex-Like” quinazoline bound to ‘STE-like kinase’: 2JAO


Is that an A-Loop in your pocket or are you just happy to see me?

 N#CC1=CC=C(NC2=NC(NC3=NNC(C4CC4)=C3)=C5C=CC=CC5=N2)C=C1

I consider these similar to VX-680.  The Takeda / BMS series likely hit Aurora quite the same.

Posted in PDB | 2 Comments »

 
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