BMS-354825 vs. VX-680
Posted by kinasepro on November 24, 2006
At least the PDB gave us something to look at a few days ago. Here’s a super-cool alignment of dasatinib in Abl to VX-680 in an abl mutant.
KinasePro
Kinase Chemistry – Just a year and a half behind the times.
Journals (beta)- Synthesis and Biological Evaluation of 3,6-Diamino-1H-pyrazolo[3,4-b]pyridine Derivatives as Protein Kinase Inhibitors
- Everolimus
- Cell cycle kinases as therapeutic targets for cancer
- 9-(Arenethenyl)purines as Dual Src/Abl Kinase Inhibitors Targeting the Inactive Conformation: Design, Synthesis, and Biological Evaluation
- Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening
- Characterizing the Effects of the Juxtamembrane Domain on Vascular Endothelial Growth Factor Receptor-2 Enzymatic Activity, Autophosphorylation, and Inhibition by Axitinib
- A Study of CDK2 Inhibitors Using a Novel 3D-QSAR Method Exploiting Receptor Flexibility
- Comparative Investigation of the ATP-Binding Site of Human and Plasmodial Glycogen Synthase Kinase-3
- 3HVC
- 3HNG
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